dorsal/arxiv
View SchemaPhysics-guided foundation model for universal speckle removal in ultrathin multimode fiber imaging
| Authors | Xianrui Zeng, Yirui Zang, Pengfei Liu, Fei Yu, Yang Yang, Tomáš Čižmár, Yang Du |
|---|---|
| Categories | |
| ArXiv ID | 2601.06448vv1 |
| URL | https://arxiv.org/abs/2601.06448 |
| License | http://arxiv.org/licenses/nonexclusive-distrib/1.0/ |
Abstract
Ultrathin multimode fibers (MMFs) promise endoscopes with hair-scale diameters for accessing sub-millimeter anatomy, but in MMF far-field imaging the required small collection aperture drives speckle-dominated measurements that rapidly degrade image fidelity. Here we present Speckle Clean Network (SCNet), a physics-guided foundation model for universal speckle removal that makes photon-limited, single-fiber collection compatible with high-fidelity reconstruction across diverse scattering conditions without target-specific retraining. SCNet combines a Mixture of Experts (MoE) architecture with material-aware routing, wavelet-based frequency decomposition to separate structure from speckle across sub-bands, and a curriculum-style optimization that progressively enforces spectral consistency before spatial fidelity. Using an ultrathin dual-fiber holographic probe, we deliver wavefront-shaped illumination through one s and collect backscattered photons through a parallel MMF. We validate SCNet on 3D plastic objects over varying working distances, resolve 5.66 lp/mm on a paper USAF target, and restore fine structures on leaves and metal surfaces. On rabbit heart and kidney tissues, SCNet improves recovery of low-contrast anatomical texture under the same ultrathin collection constraint. We further compress SCNet through multi-teacher distillation to reduce computation while preserving reconstruction quality, enabling inference at 60 FPS. This work effectively decouples image quality from probe size, establishing a speckle-free ultrathin endoscopy for stand-off imaging in confined spaces.
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"date_created": "2026-02-17T05:53:08.248000Z",
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"abstract": "Ultrathin multimode fibers (MMFs) promise endoscopes with hair-scale diameters for accessing sub-millimeter anatomy, but in MMF far-field imaging the required small collection aperture drives speckle-dominated measurements that rapidly degrade image fidelity. Here we present Speckle Clean Network (SCNet), a physics-guided foundation model for universal speckle removal that makes photon-limited, single-fiber collection compatible with high-fidelity reconstruction across diverse scattering conditions without target-specific retraining. SCNet combines a Mixture of Experts (MoE) architecture with material-aware routing, wavelet-based frequency decomposition to separate structure from speckle across sub-bands, and a curriculum-style optimization that progressively enforces spectral consistency before spatial fidelity. Using an ultrathin dual-fiber holographic probe, we deliver wavefront-shaped illumination through one s and collect backscattered photons through a parallel MMF. We validate SCNet on 3D plastic objects over varying working distances, resolve 5.66 lp/mm on a paper USAF target, and restore fine structures on leaves and metal surfaces. On rabbit heart and kidney tissues, SCNet improves recovery of low-contrast anatomical texture under the same ultrathin collection constraint. We further compress SCNet through multi-teacher distillation to reduce computation while preserving reconstruction quality, enabling inference at 60 FPS. This work effectively decouples image quality from probe size, establishing a speckle-free ultrathin endoscopy for stand-off imaging in confined spaces.",
"arxiv_id": "2601.06448",
"authors": [
"Xianrui Zeng",
"Yirui Zang",
"Pengfei Liu",
"Fei Yu",
"Yang Yang",
"Tom\u00e1\u0161 \u010ci\u017em\u00e1r",
"Yang Du"
],
"categories": [
"physics.optics"
],
"license": "http://arxiv.org/licenses/nonexclusive-distrib/1.0/",
"title": "Physics-guided foundation model for universal speckle removal in ultrathin multimode fiber imaging",
"url": "https://arxiv.org/abs/2601.06448",
"version": "v1"
},
"schema_id": "dorsal/arxiv",
"source": {
"execution_id": "96f9067c-28fe-4454-bdf8-f5c9d8d875c9",
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"type": "Model",
"variant": "snapshot-2026-01-17",
"version": "0.1.0"
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