dorsal/arxiv
View SchemaInformation-Thermodynamic Analysis of the DNA--RNA Polymerase Complex via Interface Dissipation: large Based on Observer--Observed Swap Symmetry
| Authors | Tatsuaki Tsuruyama |
|---|---|
| Categories | |
| ArXiv ID | 2601.08577vv2 |
| URL | https://arxiv.org/abs/2601.08577 |
| License | http://arxiv.org/licenses/nonexclusive-distrib/1.0/ |
Abstract
RNA polymerase (RNAP) is a molecular machine that reads information encoded in the base sequence of a DNA template while producing mechanical motion (transcription elongation; forward/backward stepping; backtracking) through chemical-potential differences of nucleoside triphosphates (NTPs) and fluctuations under external conditions. A prior work formulated a mismatch in free-energy accounting as the involvement of a term originating from genetic information (e.g.\ $k_BT\log P(N)$), and interpreted RNAP as a Maxwell's demon / Szilard-engine-like device that converts information into motion. However, in information thermodynamics, the bookkeeping of information and dissipation can depend on how one partitions the composite system into a device and a target (observer/observed labeling).
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"abstract": "RNA polymerase (RNAP) is a molecular machine that reads information encoded in the base sequence of a DNA template while producing mechanical motion (transcription elongation; forward/backward stepping; backtracking) through chemical-potential differences of nucleoside triphosphates (NTPs) and fluctuations under external conditions. A prior work formulated a mismatch in free-energy accounting as the involvement of a term originating from genetic information (e.g.\\ $k_BT\\log P(N)$), and interpreted RNAP as a Maxwell\u0027s demon / Szilard-engine-like device that converts information into motion. However, in information thermodynamics, the bookkeeping of information and dissipation can depend on how one partitions the composite system into a device and a target (observer/observed labeling).",
"arxiv_id": "2601.08577",
"authors": [
"Tatsuaki Tsuruyama"
],
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"physics.bio-ph"
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"license": "http://arxiv.org/licenses/nonexclusive-distrib/1.0/",
"title": "Information-Thermodynamic Analysis of the DNA--RNA Polymerase Complex via Interface Dissipation: large Based on Observer--Observed Swap Symmetry",
"url": "https://arxiv.org/abs/2601.08577",
"version": "v2"
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