{
  "annotation_id": "ff74b7a0-8ac6-4d9b-a846-9e11044057bc",
  "date_created": "2026-02-17T05:53:12.644000Z",
  "date_modified": "2026-02-17T05:53:12.644000Z",
  "file_hash": "884a19ac0e8a162d60f25cee61236dfea75ed8255d8ec5a6bb07e3937832bec9",
  "private": false,
  "record": {
    "abstract": "We study the problem of estimating the mutation rate between two sequences from noisy sequencing reads. Existing alignment-free methods typically assume direct access to the full sequences. We extend these methods to the sequencing framework, where only noisy reads from the sequences are observed. We use a simple model in which both mutations and sequencing errors are substitutions. We propose multiple estimators, provide theoretical guarantees for one of them, and evaluate the others through simulations.",
    "arxiv_id": "2601.07546",
    "authors": [
      "Shiv Pratap Singh Rathore",
      "Navin Kashyap"
    ],
    "categories": [
      "cs.IT",
      "math.IT",
      "q-bio.GN"
    ],
    "license": "http://arxiv.org/licenses/nonexclusive-distrib/1.0/",
    "title": "Estimators for Substitution Rates in Genomes from Read Data",
    "url": "https://arxiv.org/abs/2601.07546",
    "version": "v1"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "0b14db05-9495-43cf-9384-a536bb07e294",
    "id": "arXiv Dataset",
    "type": "Model",
    "variant": "snapshot-2026-01-17",
    "version": "0.1.0"
  },
  "user_id": 1000002
}